Hair loss tied to genetic defect in study in Russia

Scientists have identified a genetic defect in some people who have trouble growing hair, opening a new avenue for research on treatments for baldness, according to a study in tomorrow's edition of the journal Science.

An enzyme called lipase H may help hair grow and develop, researchers wrote. A specific gene, LIPH, which allows the body to produce the enzyme, is defective in some members of Russia's Chuvash and Mari populations, in which even young girls sometimes inherit a form of baldness, the scientists found. About one in four men begins to lose hair by age 30, and two in three will be bald or „have a balding pattern” by 60, according to the US National Institutes of Health. While drugs such as Pfizer Inc.'s Rogaine are sold to treat hair loss, the medicines don't work for everyone and the response to the products can't be predicted.

The new research „identifies a novel molecular pathway in regulation of hair growth,” said Evgeny Rogaev, the leader of the study and a geneticist at the University of Massachusetts Medical School in Worcester, in a November 7 e-mail. „Experiments in animals will be required to prove these predictions.” The search for a cure for baldness began at least 3,000 years ago. Ancient Egyptians treated hair loss with fats from crocodiles and geese, according to the Food and Drug Administration's Web site.

Genes are hereditary units, consisting of DNA, that contain the instructions used by the body to make essential substances called proteins. The scientists speculated that mutation in the gene makes the enzyme ineffective, arresting hair growth. Rogaev said he worked with colleagues in Russia, who had noticed many people in the Volga-Ural region, where Europe and Asia meet, have little or no body hair. The scientists screened about 350,000 people among the Mari and the Chuvash.

The resulting data suggest that more than 98,000 people in those groups have one copy of a mutated gene affecting lipase H production, according to the study. About 1,500 people have two copies of the defective gene. „The identification of a genetic defect in LIPH suggests that this enzyme regulates hair growth and therefore may be a potential target for the development of a therapeutic agent for the control of hair loss or growth,” the scientists wrote.

Current treatments are no blockbusters, according to analysts. „The problem is that the drugs don't work that well,” said Mike Krensavage, an analyst with Raymond James in New York, in a telephone interview. „The market would be huge if something worked.” With €228.4 million ($291.9 million) in sales last year, the hair-loss medicine Propecia was the 11th-biggest product for Merck & Co. The Whitehouse Station, New Jersey-based company had four products, unrelated to baldness, with more than €1.5 billion ($2 billion) each in sales, including the cholesterol drug Zocor. (Bloomberg)

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News Source:http://www.bbj.hu/main/news_18912_hair+loss+tied+to+genetic+defect+in+study+in+russia.html

Hair Loss Treatment for Men and Women

Provillus has been boon for many men and women who suffer from hair loss. Yes I said women too! The company has two products, one specifically designed for men and one product for women. Both products are geared to stop hair loss and also regrow hair back. Provillus works to give both men and women the nutritional needs we need for a healthy head of hair.

Female Pattern Baldness:

There is no set pattern for female hair loss. Some women don’t start to lose their hair until later on in life, others find their hair thinning while they are relatively young. There are many reasons for women to lose their hair but the most common is hereditary thinning or alopecia – it accounts for 95% of female hair loss.

Female Pattern Baldness (FPB) affects 1 out of every 4 women in the United States. Recent findings have found that the incidence of FPB has been reported to be as low as 8% and as high as 87%. And, it does appear to be as common for women as for men. Most often, menopause is the most frequent time for female hair loss to become apparent.

Provillus for Women aggressively seeds your scalp to create the optimum environment for new, healthy hairs. It supplies the proper nutrition to bring dead hair follicles back to life or prevent hair loss from occurring!

For women hair loss can be even more troubling than for men. Female hair loss is not generally accepted as part of the normal aging process. Society has come to expect a thick, luxurious head of hair as part of the attractiveness in women.

Male Pattern Baldness:

Hair loss and thinning hair have been sensitive issues for men throughout time. Recently, medical science has finally identified the main cause of hair loss. Now, it is a known medical fact that hair loss stems from both genetic and hormonal causes. Androgenetic Alopecia or "male pattern hair loss" is implicated in 95% of hair loss cases. The key is a hormonal byproduct called DHT (dihydrotestostrone). The more DHT that gets put into your body, the more your hair follicles become thinner and finer until the hair is permanently lost.

Provillus blocks DHT (dihydrotestostrone) from getting to your body, which is one of the major causes of hair loss. The Breakthrough formula of Provillus was designed to block DHT and supply the proper nutrients to your body specifically tailored to prevent hair loss and to help you regrow hair naturally. Strong, healthy hair begins with the proper nutritional building blocks. You don't have to wait until there's a problem to prevent it! Provillus supplements your body's natural supply of these nutrients and lets the tiny follicles beneath your scalp receive exactly what they need to create beautiful, full-bodied hair.

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Hair Loss Can Be Treated With Propecia

Recent study data show that there are 277 hairs per 1-inch circle more on the heads of people taking Propecia as compared to those taking a placebo at the end of five years.

That is A LOT more hair, making this hair loss treatment very effective! If you're already losing your hair and that bugs you, the sooner you start treatment the better. "It's easier to stop losing hair, than to replace hair that's gone," says Dr. Richard Strick, a dermatologist and UCLA clinical professor of dermatology.

Before a hair follicle shuts down, it first gets smaller and produces finer hair. So when you first notice that the hair on the top of your head or at your temples is finer than the neighboring hair, see a doctor. "Once the follicle has shut down it's difficult, sometimes impossible, to re-stimulate," Strick says.

Propecia is a pill for men that prevents hair loss and improves existing hair. Both drugs have side effects and problems that should be discussed with your physician. Propecia was developed to treat baldness in the top back and mid-scalp. There is no current evidence that Propecia works on the hairline or recession in the temporal areas.

Propecia is available in 30,60 and 90 pill Packs and cost between $46.00 to $117.00 and must be taken daily for the rest of your life or until more effective methods become available. Now for the surgical treatments. Hair transplants are the standard of care when it comes to treating hair loss. The best technique is one in which a strip of hair is removed from the back of the patient's head, assuming you have some to remove. This strip is then meticulously separated into hair units.

Most of the physicians recommended on this site will prescribe Propecia to halt a patient s hair loss and then restore the hair already lost with hair transplant surgery. These treatments in combination can work synergistically. The drugs work to halt the hair loss, while hair restoration surgery restores what was lost. The effectiveness of PROPECIA was demonstrated in studies of men, aged 18 to 41, with mild to moderate hair loss at the top and middle front of the head. There is not sufficient evidence that PROPECIA works for receding hairlines at the temples.

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News Source: http://www.powerhomebiz.com/News/112006/hair-loss-propecia.htm